Search Ontology:
ChEBI

nirmatrelvir

Term ID
CHEBI:170007
Synonyms
  • (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
  • nirmatrelvir
  • nirmatrelvirum
  • PF 07321332
  • PF-07321332
  • PF07321332
Definition
An azabicyclohexane that is (1R,5S)-3-azabicyclo[3.1.0]hexane substituted by {(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}aminoacyl, 3-methyl-N-(trifluoroacetyl)-L-valinamide, methyl and methyl groups at positions 2S, 3, 6 and 6, respectively. It is the first orally administered inhibitor of SARS-CoV-2 main protease developed by Pfizer and used in combination with ritonavir for the treatment of COVID-19.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_part
Phenotype
Phenotype resulting from nirmatrelvir
Phenotype where environments contain nirmatrelvir
Phenotype modified by environments containing nirmatrelvir
Human Disease Model
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