Search Ontology:
ChEBI
nirmatrelvir
- Term ID
- CHEBI:170007
- Synonyms
-
- (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
- nirmatrelvir
- nirmatrelvirum
- PF 07321332
- PF-07321332
- PF07321332
- Definition
- An azabicyclohexane that is (1R,5S)-3-azabicyclo[3.1.0]hexane substituted by {(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}aminoacyl, 3-methyl-N-(trifluoroacetyl)-L-valinamide, methyl and methyl groups at positions 2S, 3, 6 and 6, respectively. It is the first orally administered inhibitor of SARS-CoV-2 main protease developed by Pfizer and used in combination with ritonavir for the treatment of COVID-19.
- References
-
- CAS:2628280-40-8
- DrugBank:DB16691
- KEGG:D12244
- PMCID:PMC9232762
- PMCID:PMC9264725
- PMID:34687004
- PMID:35073029
- PMID:35153195
- PMID:35182772
- PMID:35183067
- PMID:35203821
- PMID:35305258
- PMID:35335157
- PMID:35389231
- PMID:35425393
- PMID:35461811
- PMID:35477935
- PMID:35505633
- PMID:35640480
- PMID:35678736
- PMID:35702394
- PMID:35845944
- PMID:36276807
- PMID:36574296
- PMID:36965419
- PMID:37074087
- PMID:37402789
- PMID:37510996
- PMID:37947496
- PMID:38257765
- PMID:38399271
- PMID:38432955
- PMID:38553607
- Wikipedia:Nirmatrelvir
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from nirmatrelvir
Phenotype where environments contain nirmatrelvir
Phenotype modified by environments containing nirmatrelvir
Human Disease / Model Data