Search Ontology:
ChEBI

AKI00000020a

Term ID
CHEBI:169940
Synonyms
  • 6-(2,6-dichlorophenyl)-2-[4-(morpholin-4-yl)anilino]imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one
  • 6-(2,6-dichlorophenyl)-2-{[4-(morpholin-4-yl)phenyl]amino}imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one
  • 7-(2,6-dichlorophenyl)-12-(4-morpholin-4-ylanilino)-2,5,7,11,13-pentazatricyclo[7.4.0.0(2,6)]trideca-1(13),3,5,9,11-pentaen-8-one
Definition
A member of the class of imidazopyrimidopyrimidines that is 5,6-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidine substituted by [4-(morpholin-4-yl)phenyl]amino, oxo and 2,6-dichlorophenyl groups at positions 2, 5 and 6, respectively. It is a potent inhibitor of Wee-1 kinase (Ki = <10 nM).
References
  • Patent:US20120220572
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from AKI00000020a
Phenotype where environments contain AKI00000020a
Phenotype modified by environments containing AKI00000020a
Human Disease / Model Data