Search Ontology:
ChEBI

monomethyl fumarate

Term ID
CHEBI:167450
Synonyms
  • (2E)-4-methoxy-4-oxobut-2-enoic acid
  • (E)-4-methoxy-4-oxobut-2-enoic acid
  • Bafiertam
  • fumarate de monomethyle
  • fumarato de monometilo
  • fumaric acid monomethyl ester
  • methyl hydrogen fumarate
  • mono-methyl fumarate
  • monomethyl fumarate
  • monomethylfumarate
  • monomethylis fumaras
Definition
A dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from monomethyl fumarate
Phenotype where environments contain monomethyl fumarate
Phenotype modified by environments containing monomethyl fumarate
Human Disease Model
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