nucleocidin

Term ID

CHEBI:166872

Synonyms

4'-C-fluoroadenosine 5'-sulfamate
4'-fluoro-5'-O-sulfamoyladenosine
4'-fluoro-5'-O-sulphamoyladenosine
[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate
[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-fluoro-3,4-dihydroxytetrahydrofuran-2-yl]methyl sulfamate
[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate
antibiotic T-3018
T-3018

Definition

A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 6-aminopurines adenosines diol organofluorine compound sulfamate ester

6-aminopurines adenosines diol organofluorine compound sulfamate ester Show first 5 Terms
has_functional_parent: adenosine

adenosine Show first 5 Terms
has_role: antibacterial agent bacterial metabolite nucleoside antibiotic protein synthesis inhibitor trypanocidal drug

antibacterial agent bacterial metabolite nucleoside antibiotic protein synthesis inhibitor trypanocidal drug Show first 5 Terms

Phenotype

Phenotype resulting from nucleocidin

Phenotype where environments contain nucleocidin

Phenotype modified by environments containing nucleocidin

Human Disease Model