terreic acid

Term ID

CHEBI:156546

Synonyms

(1R,6S)-3-hydroxy-4-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

Definition

A 2-hydroxy-1,4-benzoquinone that is 5,6-epoxy. It is a natural product of Aspergillus terreus. It has an antibacterial activity explained by its inhibitory effect on bacterial enzymes MurA and GlmU. It is an inhibitor of Bruton's tyrosine kinase, and has an anti-tumoral activity against HeLa and EAC cells.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: arene epoxide diketone monohydroxy-1,4-benzoquinones tertiary alpha-hydroxy ketone

arene epoxide diketone monohydroxy-1,4-benzoquinones tertiary alpha-hydroxy ketone Show first 5 Terms
has_functional_parent: 2-hydroxy-1,4-benzoquinone

2-hydroxy-1,4-benzoquinone Show first 5 Terms
has_role: antibacterial agent antineoplastic agent Aspergillus metabolite EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor ... Show All 7 Terms

antibacterial agent antineoplastic agent Aspergillus metabolite EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor mycotoxin Show first 5 Terms

Phenotype

Phenotype resulting from terreic acid

Phenotype where environments contain terreic acid

Phenotype modified by environments containing terreic acid

Human Disease Model