Search Ontology:
ChEBI

dihydrofolic acid

Term ID
CHEBI:15633
Synonyms
  • 7,8-Dihydrofolate
  • 7,8-Dihydrofolic acid
  • 7,8-Dihydropteroylglutamate
  • Dihydrofolate
  • Dihydrofolic acid
  • N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
  • N-(7,8-dihydropteroyl)-L-glutamic acid
Definition
A folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division and is targeted by various drugs to prevent nucleic acid synthesis.
References
  • CAS:4033-27-6
  • DrugBank:DB02015
  • KEGG:C00415
  • KNApSAcK:C00007248
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
inverse is_conjugate_base_of
is_conjugate_acid_of
Phenotype
Phenotype resulting from dihydrofolic acid
Phenotype where environments contain dihydrofolic acid
Phenotype modified by environments containing dihydrofolic acid
Human Disease Model