GSK2181236A

Term ID

CHEBI:155824

Synonyms

1-(6-{2-[({3-methyl-4'-[(trifluoromethyl)oxy]-4-biphenylyl}methyl)oxy]phenyl}-2-pyridinyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
1-[6-(2-{[3-methyl-4'-(trifluoromethoxy)[biphenyl]-4-yl]methoxy}phenyl)pyridin-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
GSK 2181236A
GSK-2181236A

Definition

A biphenyl that is 1,1'-biphenyl substituted by a methyl group at position 3, a (2-{6-[4-carboxy-5-(trifluoromethyl)-1H-pyrazol-1-yl]pyridin-2-yl}phenoxy)methyl group at position 4 and by a trifluoromethoxy at position 4'. It is a potent guanylate cyclase activator.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether biphenyls monocarboxylic acid organofluorine compound pyrazoles ... Show All 6 Terms

aromatic ether biphenyls monocarboxylic acid organofluorine compound pyrazoles pyridines Show first 5 Terms
has_role: antihypertensive agent soluble guanylate cyclase activator

antihypertensive agent soluble guanylate cyclase activator Show first 5 Terms

Phenotype

Phenotype resulting from GSK2181236A

Phenotype where environments contain GSK2181236A

Phenotype modified by environments containing GSK2181236A

Human Disease Model