zolasartan

Term ID

CHEBI:149761

Synonyms

1-((3-bromo-2-(o-1H-tetrazol-5-ylphenyl)-5-benzofuranyl)methyl)-2-butyl-4-chloroimidazole-5-carboxylic acid
1-({3-bromo-2-[2-(1H-tetrazol-5-yl)phenyl]-1-benzofuran-5-yl}methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid
GR 117289
GR 117289C
GR-117289
GR-117289C
GR117289
GR117289C
zolasartan
zolasartanum

Definition

A member of the class of 1-benzofurans that is 3-bromo-1-benzofuran which is substituted by a 2-(1H-tetrazol-5-yl)phenyl group at position 2 and by a (2-butyl-5-carboxy-4-chloro-1H-imidazol-1-yl)methyl group at position 5. It is an angiotensin II receptor type 1 (AT1) antagonist and was in clinical trials for the treatment of hypertension (now discontinued).

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 1-benzofurans biaryl imidazolyl carboxylic acid monocarboxylic acid organobromine compound ... Show All 7 Terms

1-benzofurans biaryl imidazolyl carboxylic acid monocarboxylic acid organobromine compound organochlorine compound tetrazoles Show first 5 Terms
has_role: angiotensin receptor antagonist antihypertensive agent

angiotensin receptor antagonist antihypertensive agent Show first 5 Terms
inverse is_conjugate_base_of: zolasartan(2-)

zolasartan(2-) Show first 5 Terms
is_conjugate_acid_of: zolasartan(2-)

zolasartan(2-) Show first 5 Terms

Phenotype

Phenotype resulting from zolasartan

Phenotype where environments contain zolasartan

Phenotype modified by environments containing zolasartan

Human Disease Model