6-de(cyclopropylamino)-6-(isopropylamino)abacavir

Term ID

CHEBI:149439

Synonyms

(1S,4R)-4-[2-amino-6-[(1-methylethyl)amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol
[(1S,4R)-4-{2-amino-6-[(propan-2-yl)amino]-9H-purin-9-yl}cyclopent-2-en-1-yl]methanol
{(1S,4R)-4-[2-amino-6-(isopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol

Definition

A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by a 3-isopropoxyazetidin-1-yl group. Unlike several other synthesised abacavir analogues, it is completely deficient in T-cell reactivity with abacavir-responsive clones.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 2,6-diaminopurines

2,6-diaminopurines Show first 5 Terms
has_functional_parent: abacavir

abacavir Show first 5 Terms

Phenotype

Phenotype resulting from 6-de(cyclopropylamino)-6-(isopropylamino)abacavir

Phenotype where environments contain 6-de(cyclopropylamino)-6-(isopropylamino)abacavir

Phenotype modified by environments containing 6-de(cyclopropylamino)-6-(isopropylamino)abacavir

Human Disease Model