Search Ontology:
ChEBI

6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir

Term ID
CHEBI:149438
Synonyms
  • (1S,4R)-4-[2-amino-6-[[(1S)-1-methylpropyl]amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol
  • 6-de(cyclopropylamino)-6-(S-sec-butylamino)abacavir
  • [(1S,4R)-4-{2-amino-6-[(2S)-butan-2-ylamino]-9H-purin-9-yl}cyclopent-2-en-1-yl]methanol
Definition
A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by an (S)-sec-butylamino group. One of a series of synthesised abacavir analogues with antiviral activity found to stimulate IFN-gamma secretion in abacavir-responsive clones.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from 6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir
Phenotype where environments contain 6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir
Phenotype modified by environments containing 6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir
Human Disease Model