noribogaine

Term ID

CHEBI:146264

Synonyms

(18R)-ibogamine-12-ol
12-hydroxyibogamine
ibogamin-12-ol
O-demethylibogaine
O-desmethylibogaine
O-noribogaine

Definition

An organic heteropentacyclic compound that is ibogamine in which the indole hydrogen para to the indole nitrogen has been replaced by a hydroxy group. It is the primary (and long-lived) metabolite of ibogaine, the psychoactive indole alkaloid found in the African rainforest shrub Tabernanthe iboga.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: monoterpenoid indole alkaloid organic heteropentacyclic compound secondary amino compound tertiary amino compound

monoterpenoid indole alkaloid organic heteropentacyclic compound secondary amino compound tertiary amino compound Show first 5 Terms
has_functional_parent: ibogaine

ibogaine Show first 5 Terms
has_role: kappa-opioid receptor agonist NMDA receptor antagonist psychotropic drug serotonin uptake inhibitor

kappa-opioid receptor agonist NMDA receptor antagonist psychotropic drug serotonin uptake inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: noribogaine(1+)

noribogaine(1+) Show first 5 Terms
is_conjugate_base_of: noribogaine(1+)

noribogaine(1+) Show first 5 Terms

Phenotype

Phenotype resulting from noribogaine

Phenotype where environments contain noribogaine

Phenotype modified by environments containing noribogaine

Human Disease Model