prednisolone phosphate

Term ID

CHEBI:145705

Synonyms

11beta,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate
prednisolone 21-(dihydrogen phosphate)
prednisolone 21-monophosphate
prednisolone 21-phosphate

Definition

A synthetic glucocorticoid resulting from the formal condensation of the 21-hydroxy group of prednisolone with one of the hydroxy groups of phosphoric acid. It is a prodrug for prednisolone that is activated in vivo by phosphatases.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid 17alpha-hydroxy steroid 20-oxo steroid glucocorticoid ... Show All 7 Terms

3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid 17alpha-hydroxy steroid 20-oxo steroid glucocorticoid steroid phosphate tertiary alpha-hydroxy ketone Show first 5 Terms
has_functional_parent: prednisolone

prednisolone Show first 5 Terms
has_role: anti-inflammatory agent antineoplastic agent glucocorticoid receptor agonist prodrug

anti-inflammatory agent antineoplastic agent glucocorticoid receptor agonist prodrug Show first 5 Terms
inverse is_conjugate_base_of: prednisolone phosphate(2-)

prednisolone phosphate(2-) Show first 5 Terms
is_conjugate_acid_of: prednisolone phosphate(2-)

prednisolone phosphate(2-) Show first 5 Terms

Phenotype

Phenotype resulting from prednisolone phosphate

Phenotype where environments contain prednisolone phosphate

Phenotype modified by environments containing prednisolone phosphate

Human Disease Model