N-glycolylneuraminyllactosylceramide

Term ID

CHEBI:144806

Synonyms

(2S,3R,4E)-3-hydroxy-2-(octadecanoylamino)octadec-4-en-1-yl 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside
(2S,3R,4E)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 3,5-dideoxy-5-(glycoloylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside
(5alpha,17alpha)-N-deacetyl-N-(hydroxyacetyl)-ganglioside GM3
1-O-(O-(N-(hydroxyacetyl)-alpha-neuraminosyl)-(2-3)-O-beta-D-galactopyranosyl-(1-4)-beta-D-glucopyranosyl)-ceramide
GM3-Neugc
HD3 ganglioside
N-glycoloyl-GM3
N-glycolyl-neuraminyl-lactosyl-ceramide
Neugc(alpha2-3)gal(beta1-4)glc(beta1-1)cer
Neugc-GM3

Definition

A sialotriaosylceramide in which the triaosyl group is 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl attached to the primary hydroxy function of ceramide. A tumour antigen found in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but not usually detected in normal human cells.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: sialotriaosylceramide

sialotriaosylceramide Show first 5 Terms
has_role: tumour antigen

tumour antigen Show first 5 Terms

Phenotype

Phenotype resulting from N-glycolylneuraminyllactosylceramide

Phenotype where environments contain N-glycolylneuraminyllactosylceramide

Phenotype modified by environments containing N-glycolylneuraminyllactosylceramide

Human Disease / Model Data