(R)-DRF053 hydrochloride hydrate

Term ID

CHEBI:142835

Synonyms

(2R)-2-({9-isopropyl-6-[3-(pyridin-2-yl)anilino]-9H-purin-2-yl}amino)butan-1-ol hydrochloride hydrate
(R)-DRF053.HCl.H2O
(R)-DRF053.xHCl.yH2O
2-[[9-(1-methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]- 9H-purin-2-yl]amino]-1-butanol hydrochloride hydrate

Definition

A hydrochloride and hydrate of DRF053, an analogue (and more potent version) of roscovitine - it is 2 fold more potent against cyclin dependent kinase 5 (CDK5) and >150 times more potent against CDK1. Formula C23H27N7O.xHCl.yH2O.

References

Pubchem:329798839

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrate hydrochloride

hydrate hydrochloride Show first 5 Terms
has_part: (R)-DRF053

(R)-DRF053 Show first 5 Terms
has_role: EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

EC 2.7.11.22 (cyclin-dependent kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from (R)-DRF053 hydrochloride hydrate

Phenotype where environments contain (R)-DRF053 hydrochloride hydrate

Phenotype modified by environments containing (R)-DRF053 hydrochloride hydrate

Human Disease Model