delanzomib

Term ID

CHEBI:141530

Synonyms

[(1R)-1-[[(2S,3R)-3-hydroxy-1-oxo-2-[[oxo-(6-phenyl-2-pyridyl)methyl]amino]butyl]amino]-3-methylbutyl]boronic acid
[(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridin-2-yl)carbonylamino]butanoyl]amino]-3-methyl-butyl]boronic acid
[(1R)-3-methyl-1-({N-[(6-phenylpyridin-2-yl)carbonyl]-L-threonyl}amino)butyl]boronic acid
boronic acid, ((1R)-1-(((2S,3R)-3-hydroxy-1-oxo-2-(((6-phenyl-2-pyridinyl)carbonyl)amino)butyl)amino)-3-methylbutyl)-
CEP-18770
CT-47098
delanzomib
delanzomibum

Definition

A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: C-terminal boronic acid peptide phenylpyridine secondary alcohol threonine derivative

C-terminal boronic acid peptide phenylpyridine secondary alcohol threonine derivative Show first 5 Terms
has_functional_parent: L-threonine

L-threonine Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer proteasome inhibitor

antineoplastic agent apoptosis inducer proteasome inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from delanzomib

Phenotype where environments contain delanzomib

Phenotype modified by environments containing delanzomib

Human Disease Model