Search Ontology:
ChEBI

rubimaillin

Term ID
CHEBI:141063
Synonyms
  • methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
  • mollugin
Definition
A benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from rubimaillin
Phenotype where environments contain rubimaillin
Phenotype modified by environments containing rubimaillin
Human Disease Model
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