disialosyl Gb5(2-)

Term ID

CHEBI:140624

Synonyms

5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->3)]-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1->3)-alpha-D-galacto
a globoside DSGG
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-[alpha-Neup5Ac-(2->6)]-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->1')-Cer
DSGG globoside
DSGG(2-)
N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide
V3NeuAcIV6NeuAc-Gb5Cer(2-)

Definition

A globoside that is a renal cell carcinoma (RCC)-associated antigen which mediates adhesion of RCC TOS-1 cells to certain lung tissue target cells.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: globoside glycoheptaosylceramide

globoside glycoheptaosylceramide Show first 5 Terms
has subtype: alpha-NeuAc-(2->3)-beta-D-Gal-(1->3)-[alpha-NeuAc-(2->6)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide(t18:0) alpha-NeuAc-(2->3)-beta-D-Gal-(1->3)-[alpha-NeuAc-(2->6)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-acylsphinganine alpha-NeuAc-(2->3)-beta-D-Gal-(1->3)-[alpha-NeuAc-(2->6)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-acylsphingosine

alpha-NeuAc-(2->3)-beta-D-Gal-(1->3)-[alpha-NeuAc-(2->6)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide(t18:0) alpha-NeuAc-(2->3)-beta-D-Gal-(1->3)-[alpha-NeuAc-(2->6)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-acylsphinganine alpha-NeuAc-(2->3)-beta-D-Gal-(1->3)-[alpha-NeuAc-(2->6)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-acylsphingosine Show first 5 Terms
has_functional_parent: Monosialyl-Gb5(1-)

Monosialyl-Gb5(1-) Show first 5 Terms
has_role: tumour antigen

tumour antigen Show first 5 Terms

Phenotype

Phenotype resulting from disialosyl Gb5(2-)

Phenotype where environments contain disialosyl Gb5(2-)

Phenotype modified by environments containing disialosyl Gb5(2-)

Human Disease / Model Data