Search Ontology:
ChEBI
rhosin
- Term ID
- CHEBI:137693
- Synonyms
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- (2R)-2-amino-3-(1H-indol-3-yl)-N'-[(E)-(quinoxalin-6-yl)methylidene]propanehydrazide
- (quinoxalinylmethylidene-D-tryptophanyl)hydrazide
- D-tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide
- Rho Inhibitor
- Definition
- A D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs
- References
-
- PMID:22726684
- PMID:23382194
- PMID:26482039
- PMID:27187066
- PMID:27681226
- PMID:28411215
- Reaxys:25133391
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from rhosin
Phenotype where environments contain rhosin
Phenotype modified by environments containing rhosin
Human Disease Model