imidapril

Term ID

CHEBI:135654

Synonyms

• (4S)-1-methyl-3-[(2S)-2-[N-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino]propionyl]-2-oxo-imidazolidine-4-carboxylic acid
• (4S)-3-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1-methyl-2-oxoimidazolidine-4-carboxylic acid
• (S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid
• imidapril
• imidaprilat
• imidaprilum
• tanatril

Definition

A member of the class of imidazolidines that is (4S)-1-methyl-2-oxoimidazolidine-4-carboxylic acid in which the hydrogen of the imidazolidine nitrogen has been substituted by (1S)-1-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}ethyl group. It is the prodrug for imidaprilat, an ACE inhibitor used for the treatment of chronic heart failure.

References

• CAS:89371-37-9
• CBA:639749
• DrugBank:DB11783
• Drug_Central:1424
• HMDB:HMDB0041907
• KEGG:D08068
• PMID:17094051
• PMID:20364557
• PMID:23161146
• PMID:28044266
• Reaxys:4847938
• VSDB:1837
• Wikipedia:Imidapril

Ontology

ChEBI  ( EBI )

Resources

CTD