yanuthone M

Term ID

CHEBI:133036

Synonyms

(1R,6R)-6-[(2E,6E)-11-hydroxy-3,7,11-trimethyldodeca-2,6-dien-1-yl]-3-methyl-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl acetate
yanuthone-M

Definition

A class I yanuthone that is yanuthone K in which the double bond at the terminal end of the farnesyl substituent has undergone hydration to afford the corresponding tertiary alcohol. Isolated from the filamentous fungus Aspergillus niger, it shows antifungal activity towards the pathogenic yeast Candida albicans (IC50 = 77.5 +-3.7 muM).

References

PMID:25293978
Reaxys:27991881

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate ester class I yanuthone tertiary amine

acetate ester class I yanuthone tertiary amine Show first 5 Terms
has_functional_parent: yanuthone K

yanuthone K Show first 5 Terms
has_role: antifungal agent Aspergillus metabolite

antifungal agent Aspergillus metabolite Show first 5 Terms

Phenotype

Phenotype resulting from yanuthone M

Phenotype where environments contain yanuthone M

Phenotype modified by environments containing yanuthone M

Human Disease Model