yanuthone L

Term ID

CHEBI:133034

Synonyms

(1R,2R,6R)-6-[(2E,6E,10E)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-3-methyl-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl acetate
yanuthone-L

Definition

A class I yanuthone that is yanuthone K in which a hydrogen of the pro-E methyl group at the terminus of the farnesyl substituent has been replaced by a hydroxy group. Isolated from the filamentous fungus Aspergillus niger, it shows antifungal activity towards the pathogenic yeast Candida albicans (IC50 = 17.0 +-1.9 muM).

References

PMID:25293978
Reaxys:27991880

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate ester class I yanuthone primary alcohol

acetate ester class I yanuthone primary alcohol Show first 5 Terms
has_functional_parent: yanuthone K

yanuthone K Show first 5 Terms
has_role: antifungal agent Aspergillus metabolite

antifungal agent Aspergillus metabolite Show first 5 Terms

Phenotype

Phenotype resulting from yanuthone L

Phenotype where environments contain yanuthone L

Phenotype modified by environments containing yanuthone L

Human Disease Model