Search Ontology:
ChEBI
fosinoprilat
- Term ID
- CHEBI:116962
- Synonyms
-
- (2S,4S)-4-cyclohexyl-1-{2-[hydroxy(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylic acid
- (2S,4S)-4-cyclohexyl-1-{2-[hydroxy-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid
- (4S)-4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-L-proline
- (4S)-4-cyclohexyl-1-{[hydroxy(4-phenylbutyl)phosphoryl]acetyl}-L-proline
- 4-Cyclohexyl-1-{2-[hydroxy-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid
- fosinopril diacid
- fosinoprilat
- fosinoprilatum
- fosinoprilic acid
- Definition
- A phosphinic acid-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. An inhibitor of angiotensin converting enzyme (ACE), it is used as the phosphinate ester pro-drug fosinopril for treatment of hypertension and chronic heart failure.
- References
-
- Beilstein:6492772
- CAS:95399-71-6
- KEGG:D03772
- PMID:10606834
- PMID:17482898
- PMID:7751424
- PMID:9549638
- Reaxys:6492772
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse has_functional_parent
-
Phenotype
Phenotype resulting from fosinoprilat
Phenotype where environments contain fosinoprilat
Phenotype modified by environments containing fosinoprilat
Human Disease / Model Data