Search Ontology:
ChEBI

fosinoprilat

Term ID
CHEBI:116962
Synonyms
  • (2S,4S)-4-cyclohexyl-1-{2-[hydroxy(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylic acid
  • (2S,4S)-4-cyclohexyl-1-{2-[hydroxy-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid
  • (4S)-4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-L-proline
  • (4S)-4-cyclohexyl-1-{[hydroxy(4-phenylbutyl)phosphoryl]acetyl}-L-proline
  • 4-Cyclohexyl-1-{2-[hydroxy-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid
  • fosinopril diacid
  • fosinoprilat
  • fosinoprilatum
  • fosinoprilic acid
Definition
A phosphinic acid-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. An inhibitor of angiotensin converting enzyme (ACE), it is used as the phosphinate ester pro-drug fosinopril for treatment of hypertension and chronic heart failure.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from fosinoprilat
Phenotype where environments contain fosinoprilat
Phenotype modified by environments containing fosinoprilat
Human Disease / Model Data