EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor

Term ID

CHEBI:102248

Synonyms

EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors
EC 1.14.11.29 inhibitor
EC 1.14.11.29 inhibitors
HIF hydroxylase inhibitor
HIF hydroxylase inhibitors
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
prolyl 4-hydroxylase inhibitor
prolyl 4-hydroxylase inhibitors

Definition

An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor

EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor Show first 5 Terms
inverse has_role: daprodustat dimethyloxalylglycine roxadustat

daprodustat dimethyloxalylglycine roxadustat Show first 5 Terms

Phenotype

Phenotype resulting from EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor

Phenotype where environments contain EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor

Phenotype modified by environments containing EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor

Human Disease Model