Search Ontology:
ChEBI
zileuton
- Term ID
- CHEBI:10112
- Synonyms
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- (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
- 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
- Leutrol
- N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
- N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
- zileuton
- zileutonum
- Zyflo
- Definition
- A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
- References
-
- CAS:111406-87-2
- DrugBank:DB00744
- Drug_Central:2862
- KEGG:D00414
- LINCS:LSM-5084
- PMID:19309543
- PMID:19645854
- PMID:20204486
- PMID:20436887
- Reaxys:4869674
- Wikipedia:Zileuton
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_parent_hydride
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- has_role
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Phenotype
Phenotype resulting from zileuton
Phenotype where environments contain zileuton
Phenotype modified by environments containing zileuton
Human Disease Model