norfloxacin

Term ID

CHEBI:100246

Synonyms

• 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure
• 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• NFLX
• norfloxacin
• norfloxacine
• norfloxacino
• norfloxacinum

Definition

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

References

• CAS:70458-96-7
• DrugBank:DB01059
• Drug_Central:1967
• Gmelin:1576626
• HMDB:HMDB0015192
• KEGG:C06687
• KEGG:D00210
• LINCS:LSM-5286
• PMID:3317294
• PMID:3908074
• PMID:6211142
• PMID:6224685
• PMID:6234465
• PMID:6454381
• PMID:6461606
• Patent:BE863429
• Patent:DE2840910
• Patent:US4146719
• Patent:US4292317
• Reaxys:567897
• VSDB:1831
• Wikipedia:Norfloxacin

Ontology

ChEBI  ( EBI )

Resources

CTD