| Term: | liver cell surface receptor signaling pathway via STAT |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | liver |
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| Synonyms: | |
| Definition: | Solid compound organ with three lobes that has many functions including bile production, blood detoxification, the production of critical plasma proteins and clotting factors, complement proteins and the storage of many substances, such as lipids, amino acids, iron, and glycogen. Female fish produce vitellogenins in the liver. |
| Ontology: | Anatomy Ontology [ZFA:0000123] |
| Name: | cell surface receptor signaling pathway via STAT |
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| Synonyms: | kinase activated-STAT cascade, kinase-STAT cascade, receptor signaling pathway via STAT, STAT signalling pathway |
| Definition: | An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins. |
| Ontology: | GO: Biological Process [GO:0097696] QuickGO AmiGO |