Term: | liver intrinsic apoptotic signaling pathway by p53 class mediator |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | liver |
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Synonyms: | |
Definition: | Solid compound organ with three lobes that has many functions including bile production, blood detoxification, the production of critical plasma proteins and clotting factors, complement proteins and the storage of many substances, such as lipids, amino acids, iron, and glycogen. Female fish produce vitellogenins in the liver. |
Ontology: | Anatomy Ontology [ZFA:0000123] |
Name: | intrinsic apoptotic signaling pathway by p53 class mediator |
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Synonyms: | intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator, signal transduction by p53 class mediator resulting in induction of apoptosis |
Definition: | The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered. |
Ontology: | GO: Biological Process [GO:0072332] QuickGO AmiGO |