| Term: | spiral neuron membrane depolarization |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | spiral neuron |
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| Synonyms: | |
| Definition: | Spiral neurons are excitatory interneurons located in rhombomere 3 and have contralateral projections that cross the midline forming commissures in rhombomere 3. After crossing the midline the two commissures fuse and project caudally synapsing with the Mauthner neuron. As they enter the axon cap, spiral fiber neurons lose their myelin and wrap around the axon hillock in a stereotyped spiral, where they make both electrical and glutamatergic synapses on the M cell axon close to the M-cell soma and with one another. Spiral neurons produced biphasic excitatory postsynaptic potentials (EPSPs) in the contralateral M-cell with a short latency. |
| Ontology: | Anatomy Ontology [ZFA:0005874] |
| Name: | membrane depolarization |
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| Synonyms: | |
| Definition: | The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. |
| Ontology: | GO: Biological Process [GO:0051899] QuickGO AmiGO |