| Term: | neural crest negative regulation of gene expression via chromosomal CpG island methylation |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | neural crest |
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| Synonyms: | |
| Definition: | A cell population arising from the dorsolateral aspect of the central nervous system primordium during the segmentation period, and later migrating along stereotyped pathways to give rise to a diverse and well-defined set of cell types including pigment cells, peripheral neurons and glia, and head cartilage. |
| Ontology: | Anatomy Ontology [ZFA:0000045] |
| Name: | negative regulation of gene expression via chromosomal CpG island methylation |
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| Synonyms: | DNA hypermethylation of CG island, DNA hypermethylation of CpG island, epigenetic regulation of gene expression via CpG island hypermethylation, hypermethylation of CpG island, negative regulation of gene expression via chromosomal CG dinucleotide methylation, negative regulation of gene expression via chromosomal CpG dinucleotide methylation, negative regulation of gene expression via chromosomal DNA cytosine methylation, negative regulation of gene expression via CpG island hypermethylation, negative regulation of gene expression via CpG island methylation |
| Definition: | An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes. |
| Ontology: | GO: Biological Process [GO:0044027] QuickGO AmiGO |