| Term: | pyramidal cell dendritic spine |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | pyramidal cell |
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| Synonyms: | pyramidal cells |
| Definition: | A projection neuron in the cerebral cortex and the hippocampus. Pyramidal cells have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their cortical region. |
| Ontology: | Anatomy Ontology [ZFA:0009273] |
| Name: | dendritic spine |
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| Synonyms: | branched dendritic spine, dendrite spine, mushroom dendritic spine, sessile dendritic spine, stubby dendritic spine, thin dendritic spine |
| Definition: | A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. |
| Ontology: | GO: Cellular Component [GO:0043197] QuickGO AmiGO |