Term: | glomerular basement membrane glomerular endothelium fenestra |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | glomerular basement membrane |
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Synonyms: | glomerular filtration membrane |
Definition: | Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space. |
Ontology: | Anatomy Ontology [ZFA:0005285] |
Name: | glomerular endothelium fenestra |
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Synonyms: | GEnC fenestration, glomerular endothelial cell fenestration |
Definition: | A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. |
Ontology: | GO: Cellular Component [GO:0036053] QuickGO AmiGO |