| Term: | keratinocyte rough endoplasmic reticulum |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | keratinocyte |
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| Synonyms: | keratinocytes |
| Definition: | An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
| Ontology: | Anatomy Ontology [ZFA:0009158] |
| Name: | rough endoplasmic reticulum |
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| Synonyms: | RER, rough ER |
| Definition: | The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. |
| Ontology: | GO: Cellular Component [GO:0005791] QuickGO AmiGO |