Term: | hematopoietic multipotent progenitor cell epithelial to mesenchymal transition |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | hematopoietic multipotent progenitor cell |
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Synonyms: | hemopoietic progenitor cell |
Definition: | A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. |
Ontology: | Anatomy Ontology [ZFA:0009354] |
Name: | epithelial to mesenchymal transition |
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Synonyms: | EMT, epithelial-mesenchymal transition, mesenchymal cell differentiation from epithelial cell |
Definition: | A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. |
Ontology: | GO: Biological Process [GO:0001837] QuickGO AmiGO |