Term: | neural plate border transcription coregulator binding |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | neural plate border |
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Synonyms: | |
Definition: | Region of the neural plate that will give rise to the neural crest. The neural plate border includes progenitors for the dorsal neural tube, the neural crest, and placodes. It is a broad competence domain, established between neural and non-neural ectoderm within which subtle and sequential cell autonomous and non-cell autonomous molecular interactions will progressively define the neural crest fate from adjacent dorsal neural fates. |
Ontology: | Anatomy Ontology [ZFA:0007082] |
Name: | transcription coregulator binding |
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Synonyms: | RNA polymerase II transcription cofactor binding, RNA polymerase II transcription coregulator binding, transcription cofactor binding |
Definition: | Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery. |
Ontology: | GO: Molecular Function [GO:0001221] QuickGO AmiGO |