| Term: | testis 3,3',5-triiodo-L-thyronine |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | testis |
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| Synonyms: | testes |
| Definition: | Male reproductive organ. Adult zebrafish testes are paired organs forming elongated structures, internally organized into tubules. These tubules are formed by seminiferous epithelium containing cysts of spermatogonia and spermatocytes surrounded by somatic support cells, called Sertoli cells. Cysts are arranged around a lumen containing spermatozoa that is connected to the efferent ducts. The interstitial regions between the tubules contain the steroid-producing Leydig cells, connective tissue, and blood vessels. |
| Ontology: | Anatomy Ontology [ZFA:0000598] |
| Name: | 3,3',5-triiodo-L-thyronine |
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| Synonyms: | 3,3',5-triiodo-L-thyronine, 3,5,3'-Triiodo-L-thyronine, 3,5,3'-Triiodothyronine, 3,5,3'TRIIODOTHYRONINE, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine, L-3,5,3'-Triiodothyronine, L-T3, liothyronine, liothyroninum, liotironina, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, T3, Tertroxin, Tresitope, Triiodothyronine |
| Definition: | An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism. |
| Ontology: | ChEBI [CHEBI:18258] ( EBI ) |