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Phenotype Figure Summary
Marker:
lamb2
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Charlton-Perkins
et al.
, 2019
Figure S1
mi2001Tg + CRISPR1-lamb2 + CRISPR2-lamb2
inner limiting membrane morphology, abnormal
Muller cell cell body position, abnormal
Muller cell cell body spatial pattern, abnormal
Muller cell physical object quality, abnormal
retinal inner plexiform layer morphology, abnormal
Table S4
mi2001Tg + CRISPR1-lamb2 + CRISPR2-lamb2
inner limiting membrane broken, abnormal
Muller cell cell body spatial pattern, abnormal
Muller cell glial cell projection morphology, abnormal
Muller cell glial cell projection overlap with Muller cell glial cell projection, abnormal
Muller cell glial cell projection spatial pattern, abnormal
Muller cell physical object quality, abnormal
retinal inner plexiform layer irregular thickness, abnormal
retinal neural layer lacks parts or has fewer parts of type inner limiting membrane, abnormal
Berger
et al.
, 2012
Fig. 2
lamb2
tm272a/tm272a
(TU)
muscle dystrophic, abnormal
somite disorganized, abnormal
somite myofibril detached from somite, abnormal
Jacoby
et al.
, 2009
Fig. 1
lamb2
tm272a/tm272a
myotome skeletal muscle cell decreased amount, abnormal
myotome skeletal muscle cell degeneration, abnormal
Fig. 2
lamb2
tm272a/tm272a
muscle attachment process quality, abnormal
myotome muscle cell retracted, abnormal
slow muscle cell retracted, abnormal
Fig. 3
lamb2
tm272a/tm272a
vertical myoseptum basement membrane malformed, abnormal
vertical myoseptum malformed, abnormal
Fig. 4
WT + MO3-lamb2
, 
lamb2
tm272a/tm272a
myotome skeletal muscle cell decreased amount, abnormal
myotome skeletal muscle cell degeneration, abnormal
Fig. 6
lamb2
tm272a/tm272a
muscle attachment process quality, abnormal
myotome muscle cell retracted, abnormal
myotome myoseptum mislocalised, abnormal
vertical myoseptum malformed, abnormal
Fig. 7
WT + MO3-lamb2
, 
lamb2
tm272a/tm272a
muscle attachment process quality, abnormal
myotome muscle cell retracted, abnormal
myotome myoseptum mislocalised, abnormal
Fig. 8
lamb2
tm272a/tm272a
muscle attachment process quality, abnormal
myotome muscle cell retracted, abnormal
myotome myoseptum mislocalised, abnormal
skeletal muscle cell sarcolemma broken, abnormal
Phenotype Annotation (1994-2006)
Fig. for (te234)
lamb2
te234/te234
musculoskeletal movement disrupted, abnormal
notochord quality, abnormal
somite degenerate, abnormal
whole organism lethal (sensu genetics), abnormal
Fig. for (tm272a)
lamb2
tm272a/tm272a
musculoskeletal movement disrupted, abnormal
somite degenerate, abnormal
trunk musculature quality, abnormal
whole organism lethal (sensu genetics), abnormal
Fig. for (tz212)
lamb2
tz212/tz212
musculoskeletal movement disrupted, abnormal
notochord quality, abnormal
somite degenerate, abnormal
whole organism lethal (sensu genetics), abnormal
Granato
et al.
, 1996
Fig. 3
lamb2
te234/te234
myotome degenerate, abnormal
Table 1
lamb2
tz212/tz212
, 
lamb2
te234/te234
, 
lamb2
tm272a/tm272a
larval locomotory behavior decreased rate, abnormal
myotome degenerate, abnormal
myotome refractivity, abnormal
notochord morphology, abnormal
somite degenerate, abnormal
thigmotaxis decreased rate, abnormal
whole organism viability, abnormal
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