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Phenotype Figure Summary
Marker:
polr1d
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Calo
et al.
, 2018
Fig. 4
polr1d
hi2393Tg/hi2393Tg
ceratobranchial cartilage malformed, abnormal
ceratohyal cartilage decreased length, abnormal
ceratohyal cartilage malformed, abnormal
head ab6-h2afx labeling increased amount, abnormal
Meckel's cartilage malformed, abnormal
palatoquadrate cartilage malformed, abnormal
Noack Watt
et al.
, 2016
Fig. 2
polr1d
hi2393Tg/hi2393Tg
cranium necrotic, abnormal
eye decreased size, abnormal
head decreased size, abnormal
mandibular arch skeleton decreased size, abnormal
midbrain hindbrain boundary morphology, abnormal
swim bladder uninflated, abnormal
Fig. 3
polr1d
hi2393Tg/hi2393Tg
ceratobranchial cartilage decreased size, abnormal
ceratohyal cartilage polarity, abnormal
cranial cartilage hypoplastic, abnormal
ethmoid cartilage hypoplastic, abnormal
mandibular arch skeleton decreased size, abnormal
Meckel's cartilage decreased size, abnormal
palatoquadrate cartilage decreased size, abnormal
Fig. 4
polr1d
hi2393Tg/hi2393Tg
pharyngeal arch neural crest cell
dlx2a
expression decreased distribution, abnormal
pharyngeal arch neural crest cell
dlx2a
expression spatial pattern, abnormal
Fig. 5
polr1d
hi2393Tg/hi2393Tg
; y1Tg
pharyngeal arch 1 decreased size, abnormal
pharyngeal arch 2 decreased size, abnormal
pharyngeal arch hypoplastic, abnormal
Fig. 6
polr1d
hi2393Tg/hi2393Tg
cranium apoptotic process increased occurrence, abnormal
neuroepithelial cell apoptotic, abnormal
whole organism
tp53
expression increased amount, abnormal
Fig. 7
polr1d
hi2393Tg/hi2393Tg
ribosome biogenesis disrupted, abnormal
rRNA transcription disrupted, abnormal
Fig. S2
polr1d
hi2393Tg/hi2393Tg
cartilage development disrupted, abnormal
ceratobranchial 5 tooth hypoplastic, abnormal
ceratobranchial cartilage decreased size, abnormal
ceratohyal cartilage polarity, abnormal
opercle hypoplastic, abnormal
ossification disrupted, abnormal
parasphenoid ossified, abnormal
Fig. S4
polr1d
hi2393Tg/hi2393Tg
; ir937Tg
neuroepithelial cell apoptotic, abnormal
Fig. S5
polr1d
hi2393Tg/hi2393Tg
pharyngeal arch 1 cell population proliferation decreased occurrence, abnormal
pharyngeal arch 2 cell population proliferation decreased occurrence, abnormal
Phenotype Annotation (1994-2006)
Fig. for (hi2393)
polr1d
hi2393Tg
brain necrotic, abnormal
eye decreased size, abnormal
gut quality, abnormal
heart quality, abnormal
liver quality, abnormal
Amsterdam
et al.
, 2004
text only
polr1d
hi2393Tg/hi2393Tg
central nervous system necrotic, abnormal
eye decreased size, abnormal
gut hypoplastic, abnormal
head decreased size, abnormal
liver hypoplastic, abnormal
pericardium edematous, abnormal
yolk circular, abnormal
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