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Phenotype Figure Summary
Marker:
clrn1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Gopal
et al.
, 2019
Fig. 1
clrn1
cwr1003/cwr1003
lateral crista inner ear receptor cell stereocilium organization decreased process quality, abnormal
lateral crista stereocilium bundle malformed, abnormal
posterior lateral line neuromast detection of mechanical stimulus involved in sensory perception of sound decreased process quality, abnormal
Fig. 2
clrn1
cwr1003/cwr1003
startle response decreased occurrence, abnormal
whole organism dead, abnormal
Gopal
et al.
, 2015
Fig. 2
clrn1
cwr1004/cwr1004
, 
clrn1
cwr1003/cwr1003
, 
clrn1
cwr1002/cwr1002
, 
clrn1
cwr1001/cwr1001
startle response decreased occurrence, abnormal
swimming behavior process quality, abnormal
whole organism unbalanced, abnormal
Fig. 3
clrn1
cwr1004/cwr1004
, 
clrn1
cwr1003/cwr1003
, 
clrn1
cwr1002/cwr1002
, 
clrn1
cwr1001/cwr1001
hair cell stereocilium bundle
clrn1
expression absent, abnormal
hair cell stereocilium bundle shortened, abnormal
hair cell stereocilium bundle splayed, abnormal
Fig. 4
clrn1
cwr1001/cwr1001
hair cell decreased functionality, abnormal
neuromast hair cell action potential decreased process quality, abnormal
neuromast hair cell membrane depolarization during action potential decreased process quality, abnormal
Ogun
et al.
, 2014
Fig. 10
AB + MO1-clrn1 + MO2-clrn1 + MO3-clrn1
synaptic vesicle recycling via endosome disrupted, abnormal
Fig. 3
AB + MO1-clrn1 + MO2-clrn1 + MO3-clrn1
anterior lateral line neuromast decreased amount, abnormal
pericardium edematous, abnormal
posterior lateral line neuromast decreased amount, abnormal
trunk curved ventral, abnormal
whole organism anterior-posterior axis decreased length, abnormal
Fig. 4
AB + MO1-clrn1 + MO2-clrn1 + MO3-clrn1
neuromast hair cell decreased functionality, abnormal
Fig. 5
AB + MO1-clrn1 + MO2-clrn1 + MO3-clrn1
neuromast hair cell kinocilium decreased length, abnormal
Fig. 8
s356tTg + MO1-clrn1 + MO2-clrn1 + MO3-clrn1 (AB)
hair cell anterior macula terminal bouton increased amount, abnormal
protein localization to synapse disrupted, abnormal
Fig. 9
s356tTg + MO1-clrn1 + MO2-clrn1 + MO3-clrn1 (AB)
neuromast hair cell terminal bouton increased amount, abnormal
protein localization to synapse disrupted, abnormal
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