Publication |
Data |
|
Fish |
Anatomy
|
Castranova et al., 2016
|
Fig. 1
|
|
iars1y68/y68
, 
iars1y68/y68; la116Tg
, 
iars1y68/y68; y1Tg
|
- cranial vasculature angiogenesis increased occurrence, abnormal
- cranial vasculature angiogenic sprout increased amount, abnormal
- cranial vasculature dorsal region increased branchiness, abnormal
- cranial vasculature increased branchiness, abnormal
- eye decreased size, abnormal
- head decreased size, abnormal
- intersegmental vessel increased branchiness, abnormal
- trunk vasculature angiogenesis increased occurrence, abnormal
- trunk vasculature angiogenic sprout increased amount, abnormal
- whole organism decreased size, abnormal
|
|
Fig. 2
|
|
la116Tg + MO1-iars1
, 
iars1y68/y68; la116Tg
, 
iars1y68/y68; y1Tg
|
|
|
Fig. 3
|
|
iars1y68/y68
|
- endoplasmic reticulum unfolded protein response increased occurrence, abnormal
- head atf4a expression increased amount, abnormal
- head atf6 expression increased amount, abnormal
- head xbp1 expression increased amount, abnormal
- trunk atf4a expression increased amount, abnormal
- trunk atf6 expression increased amount, abnormal
- trunk xbp1 expression increased amount, abnormal
- whole organism atf4a expression increased amount, abnormal
- whole organism atf6 expression increased amount, abnormal
- whole organism vegfaa expression increased amount, abnormal
- whole organism xbp1 expression increased amount, abnormal
|
Kopajtich et al., 2016
|
Fig. 3
|
|
WT + MO3-iars1
, 
WT + MO2-iars1
|
|