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Phenotype Figure Summary
Marker:
irx3b
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Chambers
et al.
, 2019
Fig. 6
TU + MO2-irx3b
pronephric distal early tubule
tfap2a
expression decreased amount, abnormal
Naylor
et al.
, 2018
Fig. 4
TU + MO1-irx3b
corpuscles of Stannius increased size, abnormal
corpuscles of Stannius specification of animal organ identity increased occurrence, abnormal
pronephric distal early tubule
cdh17
expression decreased amount, abnormal
pronephric distal early tubule
slc12a1
expression absent, abnormal
pronephric distal early tubule
slc12a1
expression decreased amount, abnormal
pronephric distal early tubule
slc12a1
expression decreased distribution, abnormal
pronephric distal early tubule
stc1
expression increased distribution, abnormal
pronephric distal early tubule
stc1
expression mislocalised, abnormal
pronephric distal early tubule decreased length, abnormal
Fig. 5
nz1Tg + MO1-irx3b
, 
TU + MO1-irx3b
corpuscles of Stannius embryonic organ development decreased process quality, abnormal
corpuscles of Stannius specification of animal organ identity decreased occurrence, abnormal
pronephric distal early tubule
atp1a1a.4
expression decreased amount, abnormal
pronephric distal early tubule
stc1
expression increased distribution, abnormal
pronephric distal early tubule
stc1
expression mislocalised, abnormal
pronephric distal late tubule epithelial cell increased length, abnormal
pronephric distal late tubule increased width, abnormal
pronephric proximal straight tubule decreased width, abnormal
pronephric proximal straight tubule epithelial cell increased length, abnormal
Fig. 6
s940Tg + CRISPR1-irx3b + CRISPR2-irx3b
, 
TU + CRISPR1-irx3b + CRISPR2-irx3b
corpuscles of Stannius embryonic organ development decreased process quality, abnormal
pronephric distal early tubule
stc1
expression increased distribution, abnormal
pronephric distal early tubule
stc1
expression mislocalised, abnormal
pronephric distal early tubule cytoplasm Ab2-hnf1b labeling mislocalised, abnormal
pronephric distal early tubule Venus expression increased distribution, abnormal
pronephric distal early tubule Venus expression mislocalised, abnormal
Fig. 6-S4
irx3b
nz14/nz14
corpuscles of Stannius embryonic organ development decreased process quality, abnormal
pronephric distal early tubule
cdh17
expression decreased amount, abnormal
pronephric distal early tubule
slc12a1
expression decreased amount, abnormal
pronephric distal early tubule
stc1
expression increased distribution, abnormal
pronephric distal early tubule
stc1
expression mislocalised, abnormal
Poureetezadi
et al.
, 2016
Fig. 7
TU + MO2-irx3b
pronephric distal early tubule
slc12a1
expression absent, abnormal
pronephric distal early tubule absent, abnormal
Naylor
et al.
, 2013
Fig. 6
TU + MO1-irx3b
pronephric distal early tubule poorly differentiated, abnormal
pronephric nephron tubule development decreased process quality, abnormal
Wingert
et al.
, 2011
Fig. 7
TU + MO1-irx3b + MO2-irx3b
pronephric distal early tubule absent, abnormal
pronephric duct proximal region increased length, abnormal
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