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Phenotype Figure Summary
Marker:
hmx3a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
England
et al.
, 2020
Figure 4
hmx3a
su43Tg/su43Tg
, 
hmx3a
su3/su3
neuromast primordium migration disrupted, abnormal
otolith fused with otolith, abnormal
Figure 5
hmx3a
su3/su3
anterior macula fused with posterior macula, abnormal
inner ear
hmx3a
expression decreased amount, abnormal
inner ear anterior region
pax5
expression decreased amount, abnormal
neuroblast (sensu Vertebrata)
hmx3a
expression decreased amount, abnormal
neuromast primordium migration disrupted, abnormal
otolith fused with otolith, abnormal
spinal cord glutamatergic neuron decreased amount, abnormal
Figure 6
hmx3a
su3/su3
spinal cord GABAergic neuron
gad1b
expression increased amount, abnormal
spinal cord GABAergic neuron increased amount, abnormal
spinal cord inhibitory interneuron
slc32a1
expression increased amount, abnormal
spinal cord inhibitory interneuron increased amount, abnormal
Hartwell
et al.
, 2019
Fig 5
hmx3a
su3/su3
(AB)
inner ear morphogenesis decreased process quality, abnormal
lapillus fused with sagitta, abnormal
otic vesicle anterior region
fgf3
expression decreased amount, abnormal
otic vesicle anterior region
hmx2
expression decreased amount, abnormal
otic vesicle anterior region
hmx3a
expression decreased amount, abnormal
otic vesicle anterior region
pax5
expression decreased amount, abnormal
otic vesicle postero-medial region
hmx3a
expression mislocalised, abnormal
posterior macula fused with anterior macula, abnormal
statoacoustic (VIII) ganglion neuroblast
hmx3a
expression decreased amount, abnormal
Feng
et al.
, 2010
text only
AB + MO1-hmx3a
, 
AB + MO2-hmx3a
otolith fused with otolith, abnormal
posterior lateral line neuromast decreased amount, abnormal
whole organism balance, abnormal
whole organism decreased coordination, abnormal
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