| ZFIN ID: ZDB-EXP-241030-5 |
Experiment Conditions Description: chemical treatment by environment: triclocarban, chemical treatment by environment: Z-DEVD-FMK
| chemical treatment by environment: triclocarban |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | triclocarban |
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| Synonyms: | 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea, 1-(4-chlorophenyl)-3-(3,4-dichlorophenyl)urea, 3,4,4'-trichloro carbanilide, 3,4,4'-trichlorocarbanilide, 3,4,4'-trichlorodiphenylurea, Cutisan, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea, Nobacter, Solubacter, TCC, triclocarban, triclocarbanum |
| Definition: | A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively. |
| Ontology: | ChEBI [CHEBI:48347] ( EBI ) |
| chemical treatment by environment: Z-DEVD-FMK |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Z-DEVD-FMK |
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| Synonyms: | benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone, benzyloxycarbonyl-Asp-Glu-Val-Asp-fluoromethylketone, methyl (4S)-5-{[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino}-4-{[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methoxy-4-oxobutanoyl]amino}-5-oxopentanoate, methyl (5S,8S,11S,14S)-14-(fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate, N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-valinamide, 1,2-dimethyl ester, specific inhibitor of caspase-3, Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone, Z-DEVD-fluoromethylketone |
| Definition: | A tetrapeptide consisting of Fmoc-L-aspartic acid 4-methyl ester, methyl L-alpha-glutamic acid 5-methyl ester, L-valine and the fluoromethyl ketone derived from the 1-carboxy group of L-aspartic acid 4-methyl ester coupled in sequence. It is a specific, irreversible caspase-3 inhibitor that also shows potent inhibition of caspase-6, caspase-7, caspase-8, and caspase-10. |
| Ontology: | ChEBI [CHEBI:138013] ( EBI ) |
| Publication: | Hu et al., 2021 |
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