| ZFIN ID: ZDB-EXP-240221-3 |
Experiment Conditions Description: chemical treatment by environment: biliatresone, chemical treatment by environment: geranylgeranyl acetate
| chemical treatment by environment: biliatresone |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | biliatresone |
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| Synonyms: | 1-(4,6-dimethoxy-1,3-benzodioxol-5-yl)-2-(2-hydroxyphenyl)prop-2-en-1-one, 2-[2-(2-hydroxyphenyl)-3-oxoprop-1-en-3-yl]-1,3-dimethoxy-4,5-methylenedioxybenzene |
| Definition: | A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted at positions 5 by a 2-(2-hydroxyphenyl)-3-oxoprop-1-en-3-yl group and at positions 4 and 6 by methoxy groups. A very rare type of isoflavonoid-related 1,2-diaryl-2-propenone found in Dysphania glomulifera (red crumbweed) and D. littoralis, the enone moiety is particularly reactive, undergoing ready Michael addition of water and methanol. Biliatresone has been found to cause extrahepatic biliary atresia (obliteration or discontinuity of the extrahepatic biliary system, resulting in obstruction to bile flow) in a zebrafish model. |
| Ontology: | ChEBI [CHEBI:131631] ( EBI ) |
| chemical treatment by environment: geranylgeranyl acetate |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | geranylgeranyl acetate |
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| Synonyms: | (2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl acetate, (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl acetate, 3,7,11,15-tetramethyl-2E,6E,10E,14-hexadecatetraenyl acetate, all-trans-geranylgeranyl acetate |
| Definition: | An acetate ester obtained by the formal condensation of acetic acid with (E,E,E)-geranylgeraniol. |
| Ontology: | ChEBI [CHEBI:229666] ( EBI ) |
| Publication: | Zhao et al., 2020 |
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