| ZFIN ID: ZDB-EXP-231025-14 |
Experiment Conditions Description: chemical treatment by injection: kainate(1-), chemical treatment by environment: topiramate
| chemical treatment by injection: kainate(1-) |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | kainate(1-) |
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| Synonyms: | kainate |
| Definition: | A dicarboxylate resulting from deprotonation of both carboxy groups of kainic acid, and protonation of its amine group. Major species at pH 7.3. |
| Ontology: | ChEBI [CHEBI:156548] ( EBI ) |
| chemical treatment by environment: topiramate |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | topiramate |
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| Synonyms: | 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate, McN-4853, RWJ-17021, tipiramate, tipiramato, Topamax, topiramate, topiramato, topiramatum, TPM |
| Definition: | A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. |
| Ontology: | ChEBI [CHEBI:63631] ( EBI ) |
| Publication: | Heylen et al., 2021 |
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