ZFIN ID: ZDB-EXP-231009-8 |
Experiment Conditions Description: transection: spinal cord, chemical treatment by environment: pomalidomide
transection: spinal cord |
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Name: | transection |
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Synonyms: | |
Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
Name: | spinal cord |
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Synonyms: | medulla spinalis, spinal cord structure |
Definition: | |
Ontology: | Anatomy Ontology [ZFA:0000075] |
chemical treatment by environment: pomalidomide |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | pomalidomide |
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Synonyms: | 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione, 4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione, 4-Aminothalidomide, CC 4047, CC-4047, pomalidomide, Pomalyst |
Definition: | An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. |
Ontology: | ChEBI [CHEBI:72690] ( EBI ) |
Publication: | Cavone et al., 2021 |
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