| ZFIN ID: ZDB-EXP-221130-9 |
Experiment Conditions Description: chemical treatment by environment: N-acetyl-L-cysteine, chemical treatment by environment: clofazimine
| chemical treatment by environment: N-acetyl-L-cysteine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | N-acetyl-L-cysteine |
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| Synonyms: | (2R)-2-acetylamino-3-sulfanylpropanoic acid, (R)-2-acetylamino-3-mercaptopropanoic acid, (R)-mercapturic acid, acetilcisteina, Acetylcysteine, acetylcysteinum, L-acetylcysteine, L-alpha-acetamido-beta-mercaptopropionic acid, mercapturic acid, N-acetyl-L-(+)-cysteine, N-acetyl-L-cysteine, N-acetylcysteine, NAC |
| Definition: | An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine. |
| Ontology: | ChEBI [CHEBI:28939] ( EBI ) |
| chemical treatment by environment: clofazimine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | clofazimine |
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| Synonyms: | (4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine, 3-(p-chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine, 3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin, clofazimina, clofazimine, clofaziminum, N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine, N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine |
| Definition: | 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients. |
| Ontology: | ChEBI [CHEBI:3749] ( EBI ) |
| Publication: | Ng et al., 2020 |
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