ZFIN ID: ZDB-EXP-220721-1
Experiment Conditions Description: chemical treatment: inhibitor, chemical treatment: eliglustat
chemical treatment: inhibitor
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: inhibitor
Synonyms: inhibidor, inhibiteur, inhibitor, inhibitors
Definition: A substance that diminishes the rate of a chemical reaction.
Ontology: ChEBI [CHEBI:35222]  ( EBI )
chemical treatment: eliglustat
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: eliglustat
Synonyms: eliglustat, Genz 99067, Genz-99067, N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide
Definition: A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.
Ontology: ChEBI [CHEBI:82752]  ( EBI )
Publication: Lelieveld et al., 2019