ZFIN ID: ZDB-EXP-220721-1 |
Experiment Conditions Description: chemical treatment: inhibitor, chemical treatment: eliglustat
chemical treatment: inhibitor |
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Name: | chemical treatment |
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Synonyms: | |
Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
chemical treatment: eliglustat |
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Name: | chemical treatment |
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Synonyms: | |
Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
Name: | eliglustat |
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Synonyms: | eliglustat, Genz 99067, Genz-99067, N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide |
Definition: | A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease. |
Ontology: | ChEBI [CHEBI:82752] ( EBI ) |
Publication: | Lelieveld et al., 2019 |
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