ZFIN

ZFIN ID: ZDB-EXP-211230-2

Experiment Conditions Description: chemical treatment by environment: I-BET151

chemical treatment by environment: I-BET151

Name:	chemical treatment by environment
Synonyms:
Definition:	Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology:	Zebrafish Environment Condition Ontology [ZECO:0000238]

Name:	I-BET151
Synonyms:	7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-(pyridin-2-yl)ethyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one, 7-(3,5-dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one, 7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-3H-imidazo[4,5-c]quinolin-2-one, GSK 1210151A, GSK-1210151A, GSK1210151, GSK1210151A, I-BET 151
Definition:	A member of the class of imidazoquinolines that is 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one substituted by (1R)-1-(pyridin-2-yl)ethyl, 3,5-dimethyl-1,2-oxazol-4-yl, and methoxy groups at positions 1, 7, and 8, respectively. It is a pan-BET bromodomain inhibitor.
Ontology:	ChEBI [CHEBI:95083] ( EBI )

Publication:	Niu et al., 2016