| ZFIN ID: ZDB-EXP-211104-2 |
Experiment Conditions Description: chemical treatment: CFTRinh-172
| chemical treatment: CFTRinh-172 |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | CFTRinh-172 |
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| Synonyms: | (inh)-172, 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone, 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid, 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone, C2992_SIGMA, CFTR(inh)-172, Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172, cystic fibrosis transmembrane regulator inhibitor 172 |
| Definition: | A thiazolidinone that is 2-thioxo-4-thiazolidinone which is substituted at position 3 by a (m--trifluoromethyl)phenyl group and at position 5 by a p-carboxybenzylidene group. It is an inhibitor of cystic fibrosis transmembrane conductance regulator, a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. |
| Ontology: | ChEBI [CHEBI:131686] ( EBI ) |
| Publication: | Liu et al., 2020 |
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