| ZFIN ID: ZDB-EXP-210818-9 |
Experiment Conditions Description: chemical treatment by injection: lipopolysaccharide, chemical treatment by environment: dexamethasone, chemical treatment by environment: cortisol
| chemical treatment by injection: lipopolysaccharide |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | lipopolysaccharide |
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| Synonyms: | Lipopolysaccharide, lipopolysaccharides, LPS |
| Definition: | Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). |
| Ontology: | ChEBI [CHEBI:16412] ( EBI ) |
| chemical treatment by environment: dexamethasone |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | dexamethasone |
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| Synonyms: | (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone, 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 9alpha-fluoro-16alpha-methylprednisolone, Aeroseb-Dex, Auxiron, Azium, Calonat, Corson, Cortisumman, Decacort, Decadron, Decaject, Decalix, Decameth, Dexacortal, Dexacortin, dexametasona, dexamethasone, dexamethasonum, Dexason, Dexasone, DexPak, Diodex, fluormethylprednisolone, Hexadrol, Maxidex, Millicorten, Oradexon, Ozurdex, Solurex, Zema-Pak |
| Definition: | A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids. |
| Ontology: | ChEBI [CHEBI:41879] ( EBI ) |
| chemical treatment by environment: cortisol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | cortisol |
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| Synonyms: | (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, 17-hydroxycorticosterone, 4-pregnen-11beta,17alpha,21-triol-3,20-dione, cortisol, hidrocortisona, hydrocortisone, hydrocortisonum, Kendall's compound F, Reichstein's substance M |
| Definition: | A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. |
| Ontology: | ChEBI [CHEBI:17650] ( EBI ) |
| Publication: | Hsu et al., 2018 |
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